Eugene’s Guide to Spravato®: A Breakthrough for Treatment-Resistant Depression

A Guide for Eugene Residents Seeking Relief from Depression

If you’ve been battling depression with little to no relief from traditional medications, you’re not alone. Many individuals in Eugene and the surrounding areas are discovering new hope through Spravato® (esketamine) therapy—an innovative, FDA-approved treatment for treatment-resistant depression (TRD).

At Lonerock Clinic in Eugene, Oregon, we specialize in both ketamine therapy and Spravato treatments, helping people reclaim their lives when other treatments haven’t worked. So how do you know if Spravato is right for you?

What Is Spravato?

Spravato is a prescription nasal spray made from esketamine, a derivative of ketamine. Unlike traditional antidepressants that target serotonin or dopamine, Spravato works on the brain’s glutamate system, which is believed to help create new neural connections.

Spravato is administered in a certified medical setting under provider supervision—like at Lonerock Clinic.

Who Qualifies for Spravato Treatment?

Spravato is specifically approved for adults who:

Have treatment-resistant depression (failed 2 or more antidepressants)
Struggle with major depressive disorder (MDD) with suicidal thoughts

You may be a candidate if you've tried multiple antidepressants with no meaningful improvement or if depression continues to impact your daily functioning despite treatment.

Why Lonerock Clinic Is the Go-To for Spravato Treatment in Eugene

Lonerock Clinic is one of the few clinics in the Eugene-Springfield area offering Spravato treatment in a certified, comfortable, and supportive environment.

Our team:

Conducts a full evaluation to determine eligibility
Guides you through insurance approval and paperwork
Provides monitored, in-office Spravato administration sessions
Collaborates with your provider for continuity of care

We understand how isolating depression can be—and we’re here to help you find real, lasting relief.

What Does Spravato Feel Like?

Many of our patients describe Spravato sessions as deeply calming or introspective. Some feel lighter emotionally, while others notice a lifting of depressive symptoms within days or weeks.

What to Expect from Treatment

Each Spravato session at our Eugene clinic includes:

A brief check-in with our team
Nasal spray administration in a private treatment room
Two hours of in-office monitoring (you’ll need a ride home)
A gradual treatment plan (twice weekly for the first month, then tapering)

Many patients begin noticing improvements in mood, energy, and outlook within the first few treatments.

Does Insurance Cover Spravato?

Most major insurance plans—including some Medicare plans—may cover Spravato with prior authorization. Our clinic will help you navigate:

Coverage verification
Required documentation
Financial estimates if applicable

Serving Eugene, Springfield & Lane County

We’re proud to provide Spravato and ketamine therapy for individuals across Eugene, Springfield, Junction City, Cottage Grove, and surrounding communities. Our clinic offers personalized care in a safe, welcoming environment designed to support your healing journey.

Ready to Learn More?

If you think Spravato could be right for you—or if you're ready to explore alternatives to traditional antidepressants—we’re here to help.

📅 Schedule your consultation today with our Spravato care team in Eugene.